Cell collective migrations as an active matter and their relation to cell material properties

News

Apr/15/2022 A new paper is published (goto list):「Collective Cell Movement under Cell-Scale Tension Gradient at Tissue Interface」
J. Phys. Soc. Jpn. 91, 054802 (2022)

May/27/2021 A new paper is published (goto list):「Polarity Fluctuation Inhibition by Memory in Collective Cell Motion」
J. Phys. Soc. Jpn. 90, 054801 (2021)

May/27/2020 A new paper is published (goto list):「Adhesion-stabilizing long-distance transport of cells on tissue surface」
Phys. Rev. E 101, 052410 (2020)

Oct/1/2019 A new project is started (project3)「Control method development for interaction between migrating new neuron and scaffolding cells」

Sep/17/2019 My Collaborator Horibe's paper is published (goto list):「Curved surface geometry-induced topological change of an excitable planar wave」
Chaos 29, 093120 (2019)

Sep/6/2019 A new paper is published (goto list):「Cell Motion Alignment as Polarity Memory Effect」
Journal of Physical Society Japan 88, 103801 (2019)

Apr/1/2019 A new project is started (project2)「Symmetric Classification of Pattern Formation in Collective Cell Migration」

Apr/19/2018 A new paper is published (goto list):「Emergence of collective propulsion through cell-cell adhesion」
Phys. Rev. E 97, 042413 (2018)

Mar/24/2017 A new paper is published (goto list):「Cell-alignment patterns in the collective migration of cells with polarized adhesion」
Phys. Rev. E 95, 032415 (2017)

OLD News

Top > Cell collective migrations as an active matter and their relation to cell material properties

Active matter

Active matter is a matter with motility driven by its active stress[1].
As an example, collective cell migration mensioned below is important[2].

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Collective cell migration

In various biologycal phenomena including development, wound healing and immune response, cells exhibit a collective migration[2].
The control mechanism of the migrtion is not sufficiently known.
The collective migration is possible to be reproduced by a Potts model[3].
I attempt to application of this method to various biological systems.

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Cell as a material

Recently, the properties of cells are intensively investigated for some industrical and medical applications[4].

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Publications

K. Matsushita, K. Horibe, N. Kamamoto and K. Fujimoto, "Cell Motion Alignment as Polarity Memory Effect" Journal of the Physical Society of Japan 88(10) 103801(5)
K. Matsushita, "Emergence of collective propulsion through cell-cell adhesion" Physical Review E 97(4) (2018) 042413(5)(Apr/19/2018)(arXiv:1708.09593)
K. Matsushita, "Cell-alignment patterns in the collective migration of cells with polarized adhesion", Phys. Rev. E 95, 032415(2017).
K. Matsushita, "Collective Migration of Repulsively Interacting Cells", Proc. Sympo. Simul. Traffic Flow 21, 19 (2015)
K. Matsushita, "Model Prediction of Cell-Shape Dependence of Cell Motion" Proc. Sympo. Simul. Traffic Flow 22, (2016) 5-8

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Reference

[1]M. C. Marchetti et al., Rev. Mod. Phys. 85, 1143 (2013).
[2]E. Mehes and T. Vicsek, Integr. Bio. 6, 831 (2014).
[3]A. Anderson, K. Rejniak (Eds.), Single-Cell-Based Models in Biology and Medicine (Springer, 2007).
[4]Karen E Kasza et al., Curr. Opin. Cell Bio. 19, 101 (2007).